ChloraPrep® Patient Preoperative Skin Preparation
ChloraPrep® skin antiseptic is a preferred patient preoperative skin prep for a variety of reasons. The unique formulation, hands-free applicator and clinical evidence all contribute to its proven performance in a range of minor and major medical procedures.
Proven Solution
The 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol formulation acts fast on a broad spectrum of skin-dwelling bacteria, and keeps fighting skin-dwelling bacteria for at least 48 hours.
Proven Applicators
ChloraPrep applicators promote gentle friction scrub to help the solution penetrate the first five cell layers of the epidermis, where 80% of skin dwelling microorganisms reside. The patented ChloraPrep applicator promotes aseptic technique and reduces the risk of direct hand-to-patient contact, helping reduce the risk of cross-contamination.
ChloraPrep Skin Antiseptic outperforms Traditional Iodophors
- Rapid acting: ChloraPrep exhibits better immediate antimicrobial activity than povidone iodine alone
- Persistent: ChloraPrep skin antiseptic maintains antimicrobial activity for at least 48 hours. Free iodine, the active ingredient in povidone iodine and other iodophors, has minimal residual activity
- Broad spectrum: ChloraPrep antimicrobial activity is effective against a broad spectrum of microorganisms on the skin
- Active in protein-rich biomaterials: Remains active in the presence of blood, serum and other protein-rich biomaterials unlike traditional iodophors, which are neutralized
- Low irritation: CHG demonstrates low incidence of irritation
CHG is a preferred antiseptic
Use of Chloraprep skin antiseptic for patient preoperative skin preparation helps reduce microorganisms on patients' skin. Ideal properties for a preoperative skin antiseptic:
- Broad spectrum
- Rapid bactericidal activity
- Residual properties on the skin
- Active in the presence of biomaterial
- Low incidence of irritation or toxic responses
- None or minimal systemic absorption
ChloraPrep formulation demonstrates advanced antimicrobial action
ChloraPrep combines 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA) and provides two distinct mechanisms of action:
- IPA: Rapidly kills microorganisms by denaturing cell proteins
- CHG: Maintains persistent antimicrobial activity by disrupting the cell membrane and precipitating cell contents
Clinical studies support 2% CHG as a preferred antimicrobial
- Efficacy of 2% CHG in 70% IPA solution
Evaluation of a 2% chlorhexidine gluconate in 70% isopropyl alcohol skin antiseptic
