Gibco Insulin-Transferrin-Selenium-Sodium Pyruvate (ITS-A) (100X) 12067589 [Pack of 1]

• Used for adherent cell cultures
• Originally used with RPMI 1640 and Minimum Essential Medium (MEM), ITS-A is now routinely used with other basal media to support a wide variety of cell types in the presence of 2 to 4% FBS
• Insulin promotes glucose and amino acid uptake, lipogenesis, intracellular transport, and the synthesis of proteins and nucleic acids
• Transferrin is an iron carrier and it may also help to reduce toxic levels of oxygen radicals and peroxide
• Selenite is a cofactor for glutathione peroxidase and other proteins, and is used as an antioxidant in media
• Sodium Pyruvate is a precursor to amino acids, fatty acids, and cholesterol; it is an important intermediate in many biosynthetic pathways
• Manufactured at a cGMP compliant facility, located in Grand Island, New York, registered with the FDA as a medical device manufacturer and certified to ISO 13485 standards

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